Table 3

Therapy associated autoantibodies in 62 initially negative patients

Induction during months 0–3 of therapyInduction during follow up periodInduction throughout observation period, in total
GAD65-Abs3-150 143-160 53-160
IA2-Abs11
21OH-Abs213
TG-Abs3912
TPO-Abs44
  • 3-150 Results of the 35S assay.

  • 3-160 Only one patient tested positive by the 125I assay.

  • Abs, autoantibodies; GAD65, glutamic acid decarboxylase; IA2, protein tyrosine phosphatase; 21OH, 21-hydroxylase; TG, thyroglobulin; TPO, thyroid peroxidase.