Electron microscopy findings in the colonocytes of mast cell deficient rats (Ws/Ws) and normal littermates (+/+) after chronic stress or sham stress.
+/+ sham | +/+ stress | Ws/Ws sham | Ws/Ws stress | |
HRP-endosome area (μm2/300 μm2 cell area) | 1.7 (0.2) | 6.1 (0.8)1-150 | 1.6 (0.1) | 1.8 (0.2) |
Mitochondrial area (μm2) | 0.21 (0.04) | 0.45 (0.06)1-150 | 0.20 (0.04) | 0.18 (0.03) |
Data are shown as mean (SEM); n=4 rats/group, 15 sections/rat.
Endosomal area is expressed as total area of horseradish peroxidase (HRP) containing endosomes in an area of 300 μm2 in the apical region of the colonocytes.
Mitochondrial area is expressed as mean area of individual mitochondria within colonocytes.
↵1-150 p<0.05 compared with sham stressed and mast cell deficient rats.