Table 1

Electron microscopy findings in the colonocytes of mast cell deficient rats (Ws/Ws) and normal littermates (+/+) after chronic stress or sham stress.

+/+ sham +/+ stress Ws/Ws sham Ws/Ws stress
HRP-endosome area (μm2/300 μm2 cell area)1.7  (0.2)6.1  (0.8)1-150 1.6  (0.1)1.8  (0.2)
Mitochondrial area (μm2)0.21 (0.04)0.45 (0.06)1-150 0.20 (0.04)0.18 (0.03)
  • Data are shown as mean (SEM); n=4 rats/group, 15 sections/rat.

  • Endosomal area is expressed as total area of horseradish peroxidase (HRP) containing endosomes in an area of 300 μm2 in the apical region of the colonocytes.

  • Mitochondrial area is expressed as mean area of individual mitochondria within colonocytes.

  • 1-150 p<0.05 compared with sham stressed and mast cell deficient rats.