Table 2

Lung injury (histological evidence) in caerulein induced pancreatitis on prophylactic/therapeutic treatment with anti-cytokine induced neutrophil chemoattractant antibody (anti-CINC antibody)

ProphylacticTherapeutic
ControlCaerulein +placeboCaerulein +antibodyCaerulein +placeboCaerulein +antibody
Alveolar thickening0.4 (0.2)2.4 (0.3)2-150 0.8 (0.3)2-151 2.3 (0.3)2-150 1.0 (0.4)2-151
Inflammation0.4 (0.2)2.6 (0.2)2-150 0.9 (0.3)2-151 2.1 (0.3)2-150 1.0 (0.4)2-151
  • 2-150 p<0.05 v control.

  • 2-151 p<0.05 v respective placebo, Mann-Whitney U test.