Prothrombotic state or risk factor | No tested | No positive |
Primary myeloproliferative disorders | 61 | 31 |
Forme fruste | 15 | |
Overt form | 16 | |
G1691A factor V gene transition (factor V Leiden) | 63 | 20 |
Anticardiolipin antibodies | 63 | 9 |
Isolated protein C deficiency1-150 | 21 | 4 |
G20210A prothrombin gene transition | 47 | 3 |
Paroxysmal nocturnal haemoglobinuria | 63 | 1 |
Isolated protein S deficiency1-150 | 30 | 2 |
Inherited plasminogen deficiency1-150 | 21 | 1 |
Antithrombin deficiency | 47 | 0 |
Pregnancy | 3 | |
None found | 6 |
↵1-150 In only 21 patients without decreased levels of clotting factors could primary natural coagulation inhibitor or plasminogen deficiencies be reliably investigated. However, despite decreased coagulation factors, normal levels of antithrombin and protein S were found in 26 and nine patients, respectively.