Table 4

Interleukin 1 receptor antagonist gene (IL-1RN) genotypes of patients with ulcerative colitis (UC) and controls, odds ratios (OR), and power of association studies in Northern European Caucasian populations

				IL-1RN genotype
		UC	HC	UC			Controls
Author	OR (95%CI)	n	n	1,1	1,2	2,2		1,1	1,2	2,2	Power^4-150
Mansfield23	2.03 (1.30–3.18)	113	261	46	55	12		152	92	17	0.58
Louis26	1.38 (0.78–2.45)	113	89	65	41	7		58	25	6	0.57
Bioque27	1.35 (0.73–2.49)	111	86	59	44	8		52	27	7	0.57
Hacker28	0.66 (0.37–1.20)	57	234	35	20	2		120	101	13	0.34
Heresebach29	0.54 (0.30–0.96)	87	108	55	25	7		52	46	10	0.47
Andus30	1.70 (0.78–3.71)	54	50	21	29	4		26	22	2	0.33
Stokkers31	1.10 (0.62–1.97)	55	270	27	26	2		139	105	26	0.33
Present study	1.31 (1.01–1.69)	320	827	155	139	26		456	317	54	0.94

↵4-150 Power to detect an OR of 2.0 (see statistical methods).
HC, healthy controls.