Adverse events in the budesonide and placebo groups
| Budesonide | Placebo | |
|---|---|---|
| No of treated patients | 59 | 59 |
| Treatment failure | 13 | 32 |
| Discontinuations due to adverse events | 4 | 2 |
| Discontinuations due to other reasons | 4 | 2 |
| Most frequent adverse events | ||
| (tapering period/after tapering of prednisolone) | ||
| Cushing syndrome | 68/53 | 53/59 |
| Arthralgia | 27/26 | 22/21 |
| C-reactive protein increased | 10/13 | 17/10 |
| Abdominal pain | 8/11 | 22/15 |
| CD aggravated | 7/13 | 17/26 |
| Fever | 7/6 | 14/5 |
| Arthritis | 7/6 | 10/13 |
| Headache | 7/9 | 3/3 |
| Diarrhoea | 5/0 | 10/3 |
| Back pain | 5/6 | 7/8 |