Bacterial community cellular fatty acid (CFA) composition in the faeces of the different age groups
CFA | Children | Adults | Elderly | CDAD |
---|---|---|---|---|
Saturated straight chain | ||||
14:0 | 4.4 (1.1) | 4.1 (1.8) | 3.0 (0.9) | 2.1 (0.8) |
15:0 | 1.7 (0.5)* | 3.0 (0.8)† | 1.6 (0.4)‡ | 0.2 (0.2)* † ‡ |
16:0 | 43.9 (2.9)* † | 24.8 (3.3)* ‡ | 37.0 (3.8)‡ | 30.3 (5.6)† |
17:0 | 1.4 (0.6) | 3.4 (1.9) | 1.1 (0.7) | 1.0 (0.8) |
18:0 | 24.1 (2.3)* | 15.3 (3.5)* | 21.9 (1.7) | 16.9 (2.7) |
20:0 | 2.9 (1.1)* | 2.7 (1.6)† | 3.0 (1.0)‡ | 9.6 (3.2)* † ‡ |
Total | 79.3 (3.3)* † | 58.3 (7.5)* | 68.4 (5.7) | 60.3 (7.4)† |
Unsaturated straight chain | ||||
16:1 cis9 | 0.0 (0.0)* † ‡ | 1.1 (0.4)* | 0.4 (0.1)† | 1.1 (0.3)‡ |
18:1cis9 | 6.9 (1.8)* | 8.2 (2.3) | 6.6 (2.0) | 15.5 (4.2)* |
18:1 cis11 | 3.9 (1.0) | 6.7 (3.5) | 5.6 (1.3) | 4.9 (2.1) |
18:2cis9, 12 | 3.5 (0.9) | 8.2 (5.0) | 4.7 (2.7) | 7.9 (2.8) |
20:1 cis11 | 0.2 (0.2)* | 0.2 (0.2)† | 0.2 (0.2)‡ | 2.9 (1.3)* † ‡ |
Total | 14.6 (2.5)* | 24.5 (10.7) | 17.5 (4.6) | 32.4 (6.4)* |
Branched chain | ||||
14:0 iso | 0.0 (0.0)* | 0.2 (0.1)* † | 0.0 (0.0) | 0.0 (0.0)† |
15:0 anteiso | 2.2 (1.0)* | 2.1 (0.5)† | 1.1 (0.3)‡ | 0.0 (0.0)* † ‡ |
15:0 iso | 0.4 (0.2)* † ‡ | 0.9 (0.2)* § | 0.7 (0.2)† ¶ | 0.0 (0.0)‡ § ¶ |
16:0 iso | 0.3 (0.2) | 0.5 (0.3) | 0.4 (0.3) | 0.0 (0.0) |
17:0 anteiso | 0.4 (0.3) | 1.1 (0.7) | 0.3 (0.2) | 0.1 (0.1) |
17:0 iso | 0.2 (0.2) | 0.5 (0.3) | 0.4 (0.2) | 0.1 (0.1) |
Total | 3.3 (1.2)* | 4.8 (1.1)† | 2.5 (0.7)‡ | 0.1 (0.4)* † ‡ |
Dimethyl acyl (DMA) | ||||
14:0 DMA | 0.0 (0.0)* † | 0.6 (0.2)* ‡ | 0.3 (0.1)† | 0.1 (0.1)‡ |
15:0 anteiso DMA | 0.0 (0.0)* | 0.5 (0.1)* † ‡ | 0.0 (0.0)† | 0.0 (0.0)‡ |
16:0 DMA | 1.0 (0.3) | 2.4 (0.6) | 2.0 (0.4) | 1.4 (0.3) |
18:0 DMA | 0.0 (0.0)* † ‡ | 1.1 (0.3)* | 0.8 (0.3)† | 1.7 (0.6)‡ |
18:1cis9 DMA | 1.3 (0.3) | 1.9 (1.0) | 1.2 (0.5) | 0.5 (0.3) |
18:1 cis11 DMA | 0.0 (0.0)* † | 1.1 (0.3)* ‡ | 0.5 (0.1)† § | 0.1 (0.1)‡ § |
19cyc9,10 DMA | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) | 0.0 (0.0) |
Total | 2.3 (0.5) | 7.5 (1.9) | 4.8 (0.6) | 3.8 (0.3) |
Results are expressed as mean (SEM) percent in children (n=10), adults (n=7), elderly (n=5), and in elderly patients withClostridium difficile associated diarrhoea (CDAD, n=4).
Corresponding symbols in the same row indicate means are significantly different (p⩽0.05).