Clinical and biochemical variables (mean (SD)) for patients with non-alcoholic steatohepatitis (NASH) (n=22) and controls (n=23)
| Variable (normal range) | NASH patients | Control subjects | p Value |
|---|---|---|---|
| Age | 54 (17) | 50 (16) | 0.4 |
| BMI (19–25 kg/m2) | 30 (6) | 24 (5) | 0.002 |
| Cholesterol (<5.5 mmol/l) | 5.7 (1.3) | 5.4 (0.9) | 0.3 |
| Triglyceride (0.7–2.1 mmol/l) | 2.4 (2.1) | 1.6 (1.0) | 0.1 |
| Fasting glucose (3–5.4 mmol/l) | 6 (1.9) | ||
| Random glucose (3–7.7 mmol/l) | 5.3 (1) | ||
| AST (0–45 U/l) | 124 (159) | 19 (5) | 0.003 |
| ALT (0–55 U/l) | 153 (161) | 18 (9) | <0.001 |
| AST/ALT ratio | 0.8 (0.4) | 1.3 (0.6) | 0.008 |
| GGT (0–55 U/l) | 125 (133) | 19 (10) | <0.001 |
| ALP (30–110 U/l) | 118 (96) | 70 (23) | 0.03 |
| Bilirubin (1–20 μmol/l) | 18 (23) | 11 (5) | 0.2 |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyltransferase; ALP, alkaline phosphate.