Table 1

Clinical and biochemical variables (mean (SD)) for patients with non-alcoholic steatohepatitis (NASH) (n=22) and controls (n=23)

Variable (normal range)NASH patients Control subjects p Value
Age54  (17)50  (16)0.4
BMI (19–25 kg/m2)30 (6)24 (5)0.002
Cholesterol (<5.5 mmol/l)5.7 (1.3)5.4 (0.9)0.3
Triglyceride (0.7–2.1 mmol/l)2.4 (2.1)1.6 (1.0)0.1
Fasting glucose (3–5.4 mmol/l)6 (1.9)
Random glucose (3–7.7 mmol/l)5.3 (1)
AST (0–45 U/l)124 (159)19 (5)0.003
ALT (0–55 U/l)153 (161)18 (9)<0.001
AST/ALT ratio0.8 (0.4)1.3 (0.6)0.008
GGT (0–55 U/l)125 (133)19 (10)<0.001
ALP (30–110 U/l)118 (96)70 (23)0.03
Bilirubin (1–20 μmol/l)18 (23)11 (5)0.2
  • AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma glutamyltransferase; ALP, alkaline phosphate.