Table 5

Total 5-aminosalicylic acid (5-ASA +N-acetyl-5-ASA) faecal and urinary recovery (as percentage of ingested dose) of Asacol, Pentasa, and olsalazine in volunteers with normal or rapid transit time (TT) and in patients with inactive or active ulcerative colitis

Healthy volunteersUlcerative colitis patients
DrugNormal TTRapid TTInactiveActive
Total faecal 5-ASA
 Olsalazine4779 (53% unsplit)39–5365 (47% unsplit)
Total urinary 5-ASA
  • Data taken from references48–54