Coeliac disease versus autoimmune diseases and neonatal outcome
| Coeliac versus | Mother diabetes3-1 | Mother other AD3-2 | Father AD incl diabetes3-3 |
| Birth week, | |||
| Difference (week) | 0.70 | −0.09 | −0.83 |
| 95% CI difference | (0.13,1.27)3-150 | (−0.60, 0.42) | (−1.93, 0.26) |
| Preterm birth (<37 weeks) | |||
| Coeliacv controls (%) | 4.1v 9.1 | 4.1 v3.9 | 12.5 v 7.1 |
| OR | 0.42 | 1.04 | 2.60 |
| 95% CI OR | (0.09–2.09) | (0.23–4.76) | (0.66–10.26) |
| Birth weight | |||
| Difference (g) | −209 | −175 | −321 |
| 95% CI difference | (−403, −15)3-151 | (−356, 7) | (−549, −93)3-152 |
| LBW ⩽2499 g | |||
| Coeliac v controls (%) | 11.3 v 2.3 | 11.3v 3.6 | 11.1 v3.0 |
| OR | 5.49 | 3.46 | 4.02 |
| 95% CI OR | (1.07–28.30)3-153 | (1.24–9.65)3-154 | (0.94–17.13) |
| Birth length | |||
| Difference (cm) | −0.34 | −0.53 | −1.49 |
| 95% CI difference | (−1.19, 0.50) | (−1.20, 0.13) | (−2.52, −0.46)3-160 |
| Caesarean section | |||
| Coeliacv controls (%) | 9.4v 29.2 | 9.4 v16.9 | 7.4 v 16.1 |
| OR | 0.25 | 0.51 | 0.42 |
| 95% CI OR | (0.09–0.71)3-164 | (0.20–1.34) | (0.09–1.85) |
| Neonatal hospital care | |||
| Coeliac v controls (%) | 17.0 v 36.0 | 17.0v 12.5 | 14.8 v7.5 |
| OR | 0.36 | 1.44 | 2.13 |
| 95% CI OR | (0.16–0.84)3-161 | (0.65–3.15) | (0.65–6.98) |
OR, odds ratio; LBW, low birth weight.
Significance values:
↵3-150 p=0.017,
↵3-151 p=0.035,
↵3-152 p=0.006,
↵3-153 p=0.042,
↵3-154 p=0.024,
↵3-160 p=0.005,
↵3-164 p=0.009,
↵3-161 p=0.009.
↵3-1 Mothers with diabetes (controls, see text);
↵3-2 mothers with non-coeliac and non-diabetes autoimmune diseases (controls, see text);
↵3-3 autoimmune diseases including diabetes (controls, see text).