Table 1

Demographic, clinical, and psychological data of PCR positive and negative patients

Characteristic PCR positive
(n=87) (%)
PCR negative
(n=68) (%)
Statistical analysis
(t test or χ2)
Age at diagnosis (mean (SD)) (y)45.7  (6.0)45.8  (4.9)NS
Source of infection (HCV contaminated anti-D)87 (100)68 (100)NS
Duration of infection (y)22–2322–23NS
Alcohol >14 IU/week (%)5 (5.7)3 (4.4)NS
No of dependents (mean; range)4.1 (1–10)4.4 (1–11)NS
Marital status (%)
 Married78 (89.7)59 (86.8)NS
 Single2 (2.3)0NS
 Separated4 (4.6)8 (11.8)NS
 Widowed3 (3.4)1 (1.5)NS
Geographical region (%)
 Urban44 (50.6)28 (41.2)NS
 Rural43 (49.4)40 (58.8)NS
ALT (IU/l) at diagnosis (mean (SD))50.6 (31)25.1 (15.4)p=0.000
ALT (IU/l) after 4/5 years follow up (mean (SD))51 (37.5)22.7 (6.5)p=0.000
History of icteric hepatitis (%)3 (3.4)14 (20.6)p=0.002
Psychological well being (GHQ30) (mean (SD))15 (9.55)  (n=43)13.5 (9.84)  (n=23)NS
Anxiety (HADS) (mean (SD))9.8 (3.97)  (n=43)9.1 (6.05)  (n=23)NS
Depression (HADS) (mean (SD))7.6 (4.1)  (n=43)7.1 (5.37)  (n=23)NS
  • HCV, hepatitis C virus; PCR, polymerase chain reaction; ALT, alanine aminotransferase; GHQ, general health questionnaire; HADS, hospital anxiety and depression scale.