Histological data of PCR positive and negative patients
|
PCR
positive (n=87) | PCR negative (n=27) |
Statistical analysis t test or χ2 | ||
| HAI at diagnosis | 4.1 (1.4) (n=85) | 2.1 (1.5) | p=0.000 | |
| Fibrosis score at diagnosis | 1.1 (1.3) (n=80) | 0.15 (0.36) | p=0.000 | |
| HAI after 5 years follow up | 4.1 (1.2) (n=44) | N/A | N/A | |
| Unchanged (n (%)) | n=19 (43.2%) | |||
| Increased (n (%); mean (SD) score change) | n=15 (34.1%; 1.4 (0.6)) | |||
| Decreased (n (%); mean (SD) score change) | n=10 (22.7%; 1.8 (0.9)) | |||
| Fibrosis score after 5 years follow up | 1.0 (1.0) (n=44) | N/A | N/A | |
| Steatosis | 9 (10.3%) (n=87) | 13 (48%) | p=0.000 | |
| Mild | 44% | 69% | ||
| Moderate/severe | 56% | 31% | ||
| Iron deposition | 1+ deposition in 1 patient with HHC3-150 | 0 | NS | |
Values are mean (SD) or number (%).
↵3-150 HHC, genetic haemochromatosis which was incidentally identified in one PCR positive patient.
N/A, not applicable; PCR, polymerase chain reaction; HAI, histological activity index.