Table 6

Extrahepatic manifestations of PCR positive and negative patients

Extrahepatic manifestation PCR positive (n=79) PCR negative (n=68)
Mixed essential cryoglobulinaemia
 Total10 (12.7% of total)06-150
 Type 23
 Type 37
 Symptomatic5 (50% of cryoglobulin)
 Sicca complex3
Sicca complex
 Total6 (7.6% of total)06-150
 ANA2
 RF1
 ENA, RNP0
 Cryoglobulinaemia3
Thyroid autoantibodies (thyroglobulin and microsomal antibodies)
 Total11 (13.9%)12 (23.5%) (n= 51)
 Normal thyroid function100%83.3%
Antinuclear antibody4 (5.1%)13 (19.1%)
Rheumatoid factor3 (3.8%)0
Antimitochondrial antibody
 Total3 (3.8%)0
 Histological features of primary biliary cirrhosis0
Antismooth muscle antibody1 (1.2%)0
Glomerulonephritis00
Dermopathy0
 Porphyria cutanea tarda00
 Lichen planus00
 Purpura7 (8.8%)0
 Purpura with cryoglobulinaemia5 (6.3%)0
  • 6-150 Denotes statistical difference.

  • PCR, polmerase chain reaction.