Table 1

Portal hypotensive drugs

Drugs which reduce portal blood flow
• Agonists of angiotensin receptors
• Agonists of V1areceptors
• Agonists of endothelin receptors
• α1 Adrenoceptor agonists
• α2 Adrenoceptor agonists
• β Adrenoceptor antagonists
 Non-selective
 Cardioselective
• β2 Adrenoceptor antagonists
• Blockers of ATP sensitive K+channels
• Calcium channel activators
• Inhibitors of nitric oxide synthase
Drugs which reduce intrahepatic vascular resistance
• β2 Adrenoceptor agonists
• ETA-ETB receptor antagonists
• Nitrovasodilators
Drugs for which the mechanism of action has not been completely clarified
• α Adrenoceptor antagonists
• Antagonists of AT1 angiotensin receptors
• Angiotensin converting enzyme inhibitors
• Antiglucagon
• Calcium channel antagonists
• Chinese medecine
• Dimethylxanthine
• Diuretics
• 5-Hydroxytryptamine receptor antagonists
• Growth hormone inhibiting factors
• Natriuretic peptides
• Parathyroid hormones
• Platelet activating factor antagonists