Risk factor | n | % | Specification |
Hepatic disorders | 52 | 30 | Cirrhosis (n=37), Budd-Chiari syndrome (n=12), nodular regenerative hyperplasia (n=2), incomplete septal fibrosis (n=1) |
Abdominal inflammation | 30 | 17 | Pancreatitis (n=11), liver abscess (n=7), inflammatory bowel disease (n=6), cholangitis (n=3), umbilical vein infection (n=1), appendicitis (n=2) |
Malignancies | 41 | 24 | Hepatocellular carcinoma (n=15), pancreatic carcinoma (n=6), biliary tract carcinoma (n=3), other malignancy with liver metastases (n=6), other malignancy without liver metastases (n=11) |
Abdominal intervention | 40 | 23 | Hepatobiliary surgery (n=20), splenectomy (n=13), liver transplantation (n=3), jejunal resection (n=2), abdominal trauma (n=2) |
Hypercoagulability | 47 | 27 | Pregnancy (n=3), oral contraceptives (n=13), paroxysmal nocturnal haemoglobinuria (n=4), antiphospholipid syndrome (n=6), systemic lupus erythematosus (n=2), factor V Leiden mutation1-150 (n=6), protrombin gene mutation1-150 (n=3), protein C deficiency1-150 (n=7), protein S deficiency1-150 (n=2), antithrombin deficiency1-150 (n=1) |
Myeloproliferative syndrome | 24 | 14 | Polycythemia vera (n=12), essential thrombocytosis (n=3), myelofibrosis (n=6), myeloid leukaemia (n=1), unclassified (n=2) |
Patients can have more than one risk factor.
↵1-150 Only tested for patients from whom a blood sample could be obtained in July 1997 (n=73).