Author
|
COX-1 localisation
|
COX-2 localisation
|
Antibody used
|
Rainsford 199591
| Not detectable | Smooth muscle cells, inner circular muscle layer | Human polyclonal antibodies |
Iseki 199592
| Mucous neck cells | Surface mucus cells | Cayman antibody |
Kargman 199693
| Endothelial cells | Subset of macrophages | Cayman antibody |
Tarnawski 199694
| Surface epithelial and some glandular cells | Endothelial cells of microvessels, submucosal macrophages | Cayman antibody |
Tarnawski 199796
| Not examined | Endothelial cells of microvessels and basement membranes | Cayman antibody |
Davies 199797
| Not examined | “Superficial mucosa” | “Primary rat antibody” |
Donnelly 199798
| Parietal cells | Myofibroblasts, endothelial cells, inflammatory mononuclear cells | Cayman antibody |
Schmassmann 199876
| Mucous neck cells | Monocytes, macrophages, fibroblasts, endothelial cells at ulcer margin | Cayman antibody |
Zimmermann 199899
| Smooth muscle cells | Smooth muscle cells, fibroblasts, endothelial cells | Dianova antibody (COX-1) Cayman antibody (COX-2) |
Takahashi 1998101
| Not examined | Fibroblasts, mononuclear cells, macrophages, granulocytes | Not specified |
Fu 1999104
| Not examined | Mononuclear cells, myofibroblasts | “Primary rat antibody” |
McCarthy 1999105
| Not examined | Surface epithelial cells, parietal cells | Cayman antibodies |
Sawaoka 1998106
| Not examined | Mucous neck cells, mononuclear cells | Not specified |