Multivariable logistic regression analysis
Predictor | Estimated odds ratio | 95% CI | p Value | |
Age group (y) | <40 | Reference | ||
40–49 | 1.01 | 0.61–1.68 | ||
50–59 | 1.55 | 0.98–2.45 | ||
60–69 | 1.71 | 1.09–2.69 | ||
⩾70 | 1.72 | 1.06–2.78 | 0.04 | |
Sex | Male | Reference | ||
Female | 0.61 | 0.44–0.83 | 0.002 | |
Smoking | Non | Reference | ||
Ex | 1.13 | 0.62–1.34 | ||
Current | 0.91 | 0.75–1.45 | 0.51 | |
Alcohol | None | Reference | ||
consumption | Mild | 1.04 | 0.75–1.45 | |
Moderate | 1.45 | 0.91–2.32 | ||
Severe | 1.82 | 0.77–4.31 | 0.25 | |
H pylori−ve | Reference | |||
H pylori+ve | cagA − | 1.05 | 0.67–1.66 | |
H pylori+ve | cagA + | 0.57 | 0.41–0.80 | 0.003 |
Drug history, NSAID | None | Reference | ||
Yes | 1.54 | 0.76–3.15 | 0.24 | |
Drug history, antacids >2× week | No Yes | Reference 1.58 | 1.19 to 2.11 | 0.002 |
Intestinal metaplasia | 0 | Reference | ||
1–100 | 0.83 | 0.57–1.21 | 0.33 | |
Hiatus hernia | No | Reference | ||
Yes | 4.86 | 3.59–6.57 | <0.0001 |