Table 1

Prevalence of each autoimmune (AI) disease among coeliac disease (CD) patients and controls: 151 AI diseases in 127 of 422 patients (30%) (multiple AI diseases occurred in single patients); 70 AI diseases in 605 controls (11.57%) (p<0.00001). Excluding dermatits herpetiformis, the prevalence of AI diseases resulted in 111 AI diseases in 91 of 422 patients (21.5%) (p=0.00001 compared with controls)

AI diseases CD patients
(n (%))
Controls
(n (%))
χ2 test (p value)
IDDM16  (3.79)2  (0.33)15.341  (<0.0005)
Dermatits herpetiformis42 (9.95)0 (0)60.269 (<0.0001)
AI thyroid diseases57 (13.5)12 (2)50.852 (<0.0001)
AI hepatitis2 (0.5)1 (0.16)0.952 (NS)
AI atrophic gastritis3 (0.71)0 (0)2.218 (NS)
AI anaemia, neutropenia, thrombocytopenia7 (1.65)1 (0.16)5.371 (=0.0218)
Connective tissue diseases7 (1.65)15 (3.19)0.455 (NS)
Psoriasis13 (3.08)36 (5.95)3.897 (=0.0488)
Alopecia1 (0.24)3 (0.5)0.021 (NS)
Epilepsy with occipital calcifications3 (0.7)0 (0)2.218 (NS)
  • IDDM, insulin dependent diabetes mellitus.