Percentage of total serum bile acids (%) | Non-acromegalic control subjects (n=6) |
Acromegalic patients Not treated with OT (n=6) | Treated with LTOT (n=8) | Patients with simple constipation (n=8) | |||||||
Placebo | Cisapride | Placebo | Cisapride | Placebo | Cisapride | Placebo | Cisapride | ||||
CA | 53 (8.9) | 61 (8.9) | 34 (4.7) | 50 (6.5) | 47 (4.3) | 56 (4.9) | 29 (6.9) | 38 (8.1) | |||
DCA | 16 (1.3) | 8.8 (2.2)3-b | 24 (4.1) | 17 (3.0)3-b | 22 (2.6) | 11 (3.5)3-b | 40 (3.4) | 22 (3.4)3-a | |||
CDCA | 30 (7.9) | 27 (7.4) | 38 (7.6) | 30 (5.9) | 28 (3.3) | 32 (5.7) | 28 (5.1) | 36 (7.4) | |||
UDCA | 2.4 (0.7) | 2.7 (0.6) | 3.5 (1.0) | 2.6 (0.7) | 2.8 (1.3) | 1.6 (0.7) | 2.8 (0.6) | 3.6 (0.8) |