Regional distribution of endothelin 1 (ET-1) levels in the kidney of control rats and rats with galactosamine (GalN) induced liver/renal failure
| Kidney region | Control (n=6) (pmol/g) | GalN (n=6) (pmol/g) |
|---|---|---|
| Values are mean (SEM) values/g of wet tissue. | ||
| There were no significant differences between the two groups although there were clearly regional differences in the formation of ET-1. | ||
| Cortex | 517 (66) | 508 (54) |
| Outer medulla | 1697 (286) | 1612 (134) |
| Inner medulla | 349 (82) | 396 (55) |
| Pelvis | 845 (144) | 1085 (125) |