Univariate analysis of clinical, histological, and virological factors for responsiveness to interferon
| CR (n=44) | NR (n=77) | Odds ratio | 95% CI | p Value | |
| Sex (M/F) | 27/17 | 53/24 | 0.72 | 0.332–1.559 | 0.404 |
| Age (<50/⩾50 (y)) | 22/22 | 34/43 | 1.26 | 0.602–2.656 | 0.535 |
| Transfusion history (+/−) | 16/28 | 27/50 | 1.06 | 0.489–2.291 | 0.886 |
| Grading score2-150(1–8/9–18) | 25/19 | 40/37 | 1.22 | 0.578–2.564 | 0.605 |
| Staging score2-160(0–1/2–4) | 26/18 | 44/33 | 1.08 | 0.511–2.297 | 0.835 |
| HCV RNA (<1.0/⩾1.0 (×106eq/ml)) | 41/3 | 15/62 | 56.49 | 20.556–155.233 | <0.0001 |
| HCV subtype (W/J/2a) | 10/10/24 | 31/28/18 | 0.002 | ||
| ISDR (wild/mutation) (genotype 1b only, n=79) | 5/15 | 35/24 | 0.23 | 0.077–0.680 | 0.008 |
↵2-150 Grading score is a total of components 1, 2, and 3 of the histological activity index (HAI) score according to Knodel and colleagues.15
↵2-160 Staging score is according to Desmet and colleagues.14
CR, complete responder; NR, non-responder; HCV, hepatitis C virus; ISDR, interferon sensitivity determining region.