Mean change in symptoms from baseline (intent to treat)
| Mean (SEM) symptom score (mm) (model based change from baseline to weeks 3–4) | Placebo bid |
ABT-229 1.25 mg bid |
ABT-229 2.5 mg bid |
ABT-229 5.0 mg bid |
ABT-229 10 mg bid |
| Upper abdominal discomfort severity score | |||||
| Normal gastric emptying | −168 (26) | −114 (26) | −188 (25) | −143 (26) | −142 (26) |
| Delayed gastric emptying | −163 (47) | −168 (40) | −129 (37) | −113 (40) | −153 (38) |
| Overall2-150 | −169 (25) | −101 (25) | −155 (24) | −143 (25) | −138 (26) |
| Patient diary sum of symptom severity scores | |||||
| Normal gastric emptying | −3.8 (0.7) | −2.2 (0.6) | −3.1 (0.6) | −3.0 (0.6) | −1.9 (0.6) |
| Delayed gastric emptying | −2.8 (1.2) | −3.0 (1.0) | −2.4 (1.0) | −2.3 (1.0) | −2.9 (1.0) |
| Overall | −3.5 (0.7) | −1.8 (0.7) | −2.2 (0.6) | −2.9 (0.7) | −2.2 (0.7) |
↵2-150 Adjusting for gastric emptying status.