Serum antitoxin and vibriocidal titres after immunisation with cholera vaccine by different routes
| IgA anti-CTB titres | IgG anti-CTB titres | Vibriocidal titres | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Immunisation | H pylori status | Day 0 | Day 21 | Frequency of responders | Day 0 | Day 21 | Frequency of responders | Day 0 | Day 21 | Frequency of responders | ||
| Intestinal | + | 23 (<5–361) | 423 (121–2081) | 6/8 | 92 (18–432) | 562 (191–2006) | 5/8 | 23 (<10–240) | 132 (20–1920) | 7/8 | ||
| Intragastric | + | 44 (8–438) | 433 (237–1197) | 6/8 | 78 (30–316) | 447 (94–2053) | 7/8 | 14 (<10–40) | 43 (<10–640) | 4/8 | ||
| Peroral | − | 13 (<5–80) | 151 (<5–9228) | 6/8 | 52 (18–176) | 281 (41–10935) | 7/8 | 13 (<10–80) | 60 (<10–480) | 5/8 | ||
| Intragastric | − | 18 (10–50) | 830 (150–3790) | 4/4 | 32 (10–70) | 736 (120–4340) | 4/4 | <10 (<10–<10) | 95 (<10–640) | 3/4 | ||
Data are presented as geometric mean (range).
CTB, cholera toxin B subunit.