Relation between coffee consumption and colorectal cancer2-150
|
Colorectal n=460 (RR (95% CI)) |
Colon n=2912-160
(RR (95% CI)) | Proximal colon n=118 (RR (95% CI)) |
Distal colon n=101 (RR (95% CI)) |
Rectal n=159 (RR (95% CI)) | |
| < 1 cup/day | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) |
| 1 cup/day | 0.96 (0.66–1.40) | 0.97 (0.61–1.54) | 0.89 (0.45–1.79) | 0.84 (0.39–1.81) | 0.88 (0.45–1.73) |
| 2–3 cups/day | 0.93 (0.67–1.29) | 0.89 (0.59–1.33) | 0.80 (0.44–1.46) | 0.78 (0.41–1.50) | 1.01 (0.57–1.78) |
| 4+ cups/day | 1.04 (0.70–1.54) | 1.06 (0.65–1.72) | 1.17 (0.56–2.43) | 0.94 (0.43–2.08) | 1.06 (0.54–2.10) |
| p for trend | 0.95 | 0.97 | 0.94 | 0.80 | 0.69 |
↵2-150 Rate ratios (RR) with 95% confidence interval (CI).
Multivariate models included age in five year age groups, body mass index (quartiles), education level (less than high school, high school, and university), quartiles of intakes of energy and red meat, and quartiles of energy adjusted total fat, dietary fibre, calcium, vitamin C, folic acid, vitamin D, and alcohol.
↵2-160 72 cases of colon cancer were of unspecified location.