Hepatic metabolism measured by 31-phosphorus magnetic resonance spectroscopy ( 31P MRS)
| Jaundice group (n=10) | |||
|---|---|---|---|
| 31P MRS measurement | Healthy controls (n=10) | At presentation | After drainage |
| Data are median (interquartile range). | |||
| ††p<0.01 healthy controls versus jaundice group at presentation. | |||
| **p<0.01 jaundice group after drainage versus value at presentation. | |||
| ATP, adenosine triphosphate; Pi, inorganic phosphate; PME, phosphomonoester; PDE, phosphodiester; TP, total visible phosphate; pHic, intracellular pH. | |||
| ATP/Pi | 1.25 (1.01–1.6) | 1.4 (1.17–1.69) | 1.97 (1.4–2.48)** |
| PME/PDE | 0.38 (0.36–0.5)†† | 0.71 (0.54–0.82) | 0.93 (0.65–1.1)** |
| PME/TP % | 10.3 (8.7–11.5)†† | 15.4 (13.1–17.7) | 17.6 (14.2–18.9) |
| PDE/TP % | 25 (22.1–26.7) | 25.2 (20.5–27.4) | 19.8 (16.6–24.5)** |
| pHic | 7.32 (7.16–7.38) | 7.44 (7.29–7.47) | 7.37 (7.27–7.45) |