Thiopurine methyltransferase (TPMT) activy
| Pretreatment TPMT activity (U/ml) | Current (study) TPMT activity (U/ml) | ||||||
| Overall | Homozygous normal (>13.7) | Heterozygous intermediate (5.1–13.7) | Overall | Homozygous normal (>13.7) | Heterozygous intermediate (5.1–13.7) | ||
| No | 163 | 145 | 18 | 164 | 141 | 23 | |
| Mean (SD) | 18.5 (4.5) | 19.6 (3.5) | 10.0 (1.7) | 17.3 (3.8) | 18.4 (2.7) | 10.5 (1.7) | |
| Median | 18.7 | 19.2 | 9.8 | 17.4 | 18.0 | 9.9 | |
| IQR | 16.3, 21.0 | 17.5, 21.4 | 9.1, 11.2 | 15.7, 20.1 | 16.3, 20.1 | 9.2, 12.0 | |
| Range | 6.8, 39.1 | 13.9, 39.1 | 6.8, 12.9 | 7.9, 28.9 | 13.9, 28.9 | 7.9, 13.7 | |
IQR, interquartile range, 25th and 75th percentiles.