Trial | (n) | Pugh's grade A/B/C | Mortality | Treatment for bleeding |
Jackson 19681-150 17 | 58 | 10/23/25 | 55% | S1-150 |
Resnick 19691-150 20 | 45 | 19/20/6 | 42% | SS |
Conn19721-150 15 | 31 | 10/11/10 | 50% | Not stated |
Conn 19721-150 15 | 22 | 0/11/11 | 83% | SS |
Paquet 198230 | 36 | 9/11/16 | 64% | “Active conservative” |
Witzel 198531 | 53 | 19/25/9 | 63% | Not stated |
Koch 198632 | 30 | 16/9/5 | 70% | Not stated |
Wordehoff 198733 | 24 | 7/12/5 | 53% | VP, BT |
Pascal 19871-150 18 | 112 | 19/41/52 | 60% | “Standard treatment” |
Sauerbruch 198834 | 65 | 21/30/14 | 46% | ES, VP, BT |
Piai 198835 | 69 | 16/31/22 | 66% | Som, ES, BT, S |
Lebrec 198836 | 53 | 29/24/0 | 50% | ES, VP, BT |
Ideo 198837 | 49 | 19/19/11 | 36% | Som, BT |
Santangelo 19881-150 21 | 45 | 12/17/16 | 29% | Not stated |
Potzi 198938 | 41 | 14/14/13 | 64% | ES |
IMPP 198939 | 89 | 56/28/5 | 32% | Drugs, ES, BT |
Russo 198940 | 20 | 9/8/3 | 67% | BT, ES |
Inokuchi 199041 | 52 | 31/21/0 | 41% | ES, S |
Kobe 199042 | 33 | 10/17/6 | 58% | ES |
Andreani 199043 | 41 | 10/21/10 | 40% | VP, BT |
Triger 199144 | 35 | 14/15/6 | 29% | ES |
De Franchis 199145 | 51 | 18/22/11 | 65% | ES |
Conn 199146 | 51 | 24/24/3 | 27% | VN, ES |
Gregory 199147 | 138 | 43/59/36 | 32% | VP, BT, SS |
PROVA 19911-150 19 | 72 | 21/22/29 | 46% | ES |
Sarin 199648 | 33 | 10/13/10 | 38% | EVL, ES |
Lay 199749 | 64 | 16/23/25 | 26% | Drugs, ES, BT, S |
Lo 1999 50 | 63 | 20/25/18 | 32% | VP, EVL |
↵1-150 Studies in which Pugh's grading was not given but was estimated from data in original publication.
Emergency treatment for variceal bleeding included: ES, endoscopic sclerotherapy; EVL, endoscopic variceal band ligation; BT, balloon tamponade; SS, shunt surgery; S, surgery; Som, somatostatin; VP, vasopressin; VN, vasopressin+nitroglycerin; S1-150, transoesophageal ligation of varices in a minority of patients—details of other treatments not given.