Table 2

Regional analysis of adenoma distribution in familial adenomatous polyposis colectomy specimens. Two factor analysis of variation is summarised

Variation SS df MS F value
Between patients488.21240.698.302-150
Within patients16.0444.010.82
Residual235.4484.90
Total739.76411.56
  • SS, sum of the squared difference from the mean; df, degrees of freedom; MS, population variance estimate; F value, Fisher's statistic (ratio of population variance estimates).

  • 2-150 p<0.01: the variation between patients was significantly different owing to the effects of different APCmutations and other germline variation but neither variation within patients nor the residual was significant.