Table 1

Clinical profiles of patients affected by colon adenocarcinoma and corresponding immunohistochemical expression of transforming growth factor β1 receptor type I (TGF-β1-RI) and type II (TGF-β-RII)

TGF-β1-RI*TGF-β1-RII*
PatientSexAge (y)pTNMHistology (grading)NCaNCa
N, normal colorectal tissue; Ca, cancerous tissue.
pTNM classification: pT, extent of the primary tumour (T2, tumour invading muscularis propria; T3, tumour invading subserosa; T4, tumour directly invading other organs and/or visceral peritoneum); pN, regional lymph node metastasis (Nx, local lymph nodes not evaluable; N0, local lymph nodes without metastasis; N1, metastasis in 1–3 local lymph nodes; N2, metastasis in four or more local lymph nodes); pM, distant metastases (Mx, metastases not evaluable; M0, no metastasis; M1, presence of metastases).
Histological tumour deviation was graded as follows: G2, moderate; G3, intense.
*The number of positive TGF-β1-RI and TGF-β1-RII cells are expressed as a percentage of the total cells examined at 250× magnification (for each slide, 20 non-consecutive randomised histological fields were evaluated).
BBF46T3N2M1G254100100100
CVM50T3N0M0G2977893100
DPF46T2N0M0G2885999100
MAM68T3N0M0G210098100100
PRF61T3N2MxG2516682100
TEM80T2N0M0G2103089
BMM59T3N0M0G272100100100
CAM56T2N0M0G210010010090
DGF56T2N0M0G210014100100
PIF72T2NxM0G2100588850
CPM69T3N1MxG294610097
CGM59T3N0M0G390100100100
MBM90T3N0M0G31006100100
GSF54T4N2M1G310010010067
TZF72T4N1M0G3100210050