Table 3

Clinical details of chronic pancreatitis patients and controls, and results of screening for mutations in the PRSS1 and SPINK1 genes

PatientsControls
Values are number of patients. Note that SPINK1 mutations were detected in 14 patients and that one chronic pancreatitis patient was compound heterozygous for SPINK1 mutations as he carried both a P55S and a N34S mutation.
n 115120
Sex (M/F) 71/4455/65
Cause of chronic pancreatitis
    Alcoholic720
    Idiopathic240
    Familial100
    Miscellaneous 90
PRSS1 mutations
    N29I 30
    R122H 30
SPINK1 mutations
    N34S13
    P55S 20
    M1T 00
    L14P 00