Table 1

Biological effects of somatostatin-14 and its analogues on gastrointestinal functions6

Inhibition of:
    • hormone secretion (gastrin, cholecystokinin, secretin, insulin, glucagon and vasoactive intestinal peptide)
    • exocrine secretory responses (gastric acid secretion and exocrine pancreatic secretion)
    • motor activity (gastric emptying and gall bladder contraction)
    • nutrient absorption
    • splanchnic/portal venous blood flow
Stimulation of:
    • water and electrolyte absorption