Table 1

Effect of bile salt infusion on liver methionine adenosyltransferase (MAT) activity and liver glutathione content

Bile salt infused
TCUDCDC
†Values are expressed as pmol/min/mg protein.
‡Values are expressed as μmol/g liver.
Livers were infused for 120 minutes with 40 or 60 μmol/h of taurocholate (TC; n=5), ursodeoxycholate (UDC; n=6), or deoxycholate (DC; n=4).
*p<0.05 compared with the other groups with the same infusion rate.
MAT activity†
    Infusion rate
        40 μmol/h150.7 (5.1)284.9 (13.3)*103.8 (9.5)
        60 μmol/h162.6 (15.8)328.4 (81.1)*109.8 (21.9)
Glutathione content‡
    Infusion rate
        40 μmol/h6.22 (0.15) 7.53 (0.24)*5.21 (0.53)
        60 μmol/h6.49 (1.3)10.02 (1.0)*5.52 (0.8)