Baseline electrophysiological variables of ileal mucosa in Ussing chambers
| Colon cancer (n=13) | CD non-inflamed (n=10) | CD inflamed (n=4) | |
|---|---|---|---|
| Transepithelial potential difference (PDt), transepithelial electrical resistance (TER), and short circuit current (Isc) at the start of the experiments in specimens from patients with cancer coli, non-inflamed specimens from patients with Crohn's disease (CD), and in inflamed specimens from patients with CD. | |||
| Data are median (25–75th interquartile range) after equilibration for 40 minutes in Ussing chambers. | |||
| There were no significant differences between groups with regard to baseline electrophysiological variables. | |||
| PDt (mV) | −9.7 (−7.8 to −10.9) | −11.1 (−8.3 to −12.2) | −10.4 (−8.8 to −13.0) |
| TER (Ωcm2) | 33.7 (29.0–35.9) | 33.5 (30.0–40.1) | 34.1 (30.0–38.8) |
| Isc (μA/cm2) | 269 (236–321) | 297 (229–400) | 273 (256–318) |