Table 1

Serum levels of nitrite/nitrate (μmol/l) in patients with chronic active Crohn's disease treated with either placebo (n=10), or recombinant human interleukin 10 at 1 (n=12), 4 (n=12), 8 (n=10), or 20 (n=10) μg/kg body weight subcutaneously over 28 days

GroupDay −1Day +15Day +29p Value*Follow up week 4
Data are mean (SEM).
*Statistical analysis was performed using ANOVA.
Placebo31.6 (3.6)32.4 ( 4.0)30.4 (3.2)0.7936.4 (4.8)
1 μg/kg29.6 (4.0)38.4 (10.6)22.8 (3.2)0.2728.0 (3.6)
4 μg/kg46.0 (9.6)46.8 (10.4)43.6 (10.8)0.7938.0 (8.0)
8 μg/kg38.0 (6.4)38.8 (5.2)47.6 (8.8)0.540.0 (5.2)
20 μg/kg34.4 (6.0)39.6 (8.0)46.0 (11.6)0.2932.8 (6.8)