Table 5

Odds ratios (OR) for coeliac disease concordance among non-index twins, estimated by logistic regression

CharacteristicConcordant pairs for CDAdjusted OR (95% CI)
MZ, monozygotic, DZ, dizygotic.
95% CI, 95% confidence interval.
Zygosity and No of shared haplotypes
    DZ sharing 0 or 1 haplotype2/21 (10%) 1.0
    DZ sharing 2 haplotypes1/6 (17%) 1.4 (0.0–27.4)
    MZ15/20 (75%)17.0 (2.1–134.0)
DQ genotype
    Not DQ2 or DQ82/12 (17%) 1.0
    DQ215/29 (52%) 3.3 (0.4–30.0)
    DQ81/6 (17%) 1.4 (0.0–41.0)
Sex of the non-index twin
    Male6/22 (27%) 1.0
    Female12/25 (48%) 1.3 (0.2–8.5)
Age at enrolment (y)
    ≤105/17 (29%) 1.0
    11–309/22 (41%) 1.6 (0.2–11.0)
    >304/8 (50%) 2.2 (0.2–27.7)