Table 2

Frequency of the diverse HLA haplotypes in patients with coeliac disease (CD) and in healthy controls

Typical versus atypical
Healthy controls (n=116)Typical CD (n=79)Atypical CD (n=54)pcOR (95% CI)EF
OR, odds ratio; 95% CI, 95% confidence interval; EF, ethiological fraction.
*pc=0.0026, OR=3.38, 95% CI (1.84–6.11), EF=0.36 (typical CD v healthy controls)
†pc=0.00003, OR=5.78, 95% CI (2.74–12.06), EF=0.33 (typical CD v healthy controls)
‡pc<10-6, OR=24.28, 95% CI (10.27–56.26), EF=0.71 (atypical CD v healthy controls).
DR7/DQB1*020128 (24.13%)41 (51.89%)*13 (24%)0.023.4 (1.58–7.29)0.40
B8/DR3/DQB1*020112 (10.34%)32 (40,5%)†40 (74%)‡0.0014.19 (1.97–8.84)0.56