Grade of evidence | |
---|---|
HRT, hormone replacement therapy; *data inconsistent. | |
Grade A, meta-analysis or randomised controlled trial or at least one randomised controlled trial. | |
Grade B, from at least one well designed controlled study without randomisation, from at least one other well designed quasi-experimental study, or from well designed non-experimental descriptive studies, for example, comparative studies, correlation studies, case controlled studies. | |
Grade C, from expert committee reports/opinions/or clinical experience of authorities. | |
The table comes from the Royal College of Physician/Bone and Tooth Society updated guidelines on the “Management of osteoporosis”. | |
Alendronate | A |
Calcitonin | A* |
Calcitriol | A* |
Calcium | A |
Cessation of smoking | B |
Cyclical etidronate | A |
HRT | A |
Physical exercise | A |
Raloxifene | A |
Reduced alcohol consumption | C |
Risedronate | A |
Tibolone | A |
Vitamin D and calcium | A |