Demographic, histological, and metabolic parameters in the 19 subjects undergoing weight reduction
Alcohol intake (g/wk) | Liver histology | Waist (cm) | BMI (kg/m2) | ALT (U/l) | Insulin (mU/l) | HOMA score | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pt No | Sex | Age (y) | Viral genotype | Pre | Post | Steatosis* | Fibrosis† | Inflamm‡ | % wt loss | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post |
*Grade of steatosis (0–3). †Stage of fibrosis (modified Knodell 0–6). ‡Inflammatory score (modified Knodell 0–18). §Asian descent. ¶Recent weight gain of 10 kg. n/d, not determined. | |||||||||||||||||||
1 | M | 42 | 3 | 0 | 0 | 3 | 1 | 5 | 10.8 | 96 | 85 | 25 | 23 | 111 | 72 | 9 | 11 | 2.16 | 2.84 |
2 | M | 45 | 1 | 10 | 0 | 3 | 5 | 3 | 7.8 | 104 | 90 | 30 | 28 | 90 | 140 | n/d | 12 | n/d | 2.40 |
3 | M | 41 | 3 | 10 | 0 | 3 | 4 | 5 | 9.7 | 99 | 88 | 28 | 25 | 147 | 102 | 9 | 6 | 1.72 | 1.79 |
4 | F | 43 | 1 | 40 | 0 | 1 | 2 | 6 | 5.8 | 106 | 87 | 32 | 31 | 48 | 37 | 10 | 5 | 2.13 | 1.09 |
5 | M | 42 | 3 | 0 | 0 | 3 | 4 | 5 | 11.2 | 110 | 101 | 34 | 31 | 182 | 53 | 16 | 8 | 3.84 | 1.96 |
6 | F | 42 | 1 | 0 | 0 | 2 | 3 | 5 | 12.7 | 92 | 90 | 33 | 29 | 128 | 43 | n/d | 12 | n/d | 2.56 |
7 | M | 30 | 3 | 10 | 10 | 2 | 1 | 3 | 8.2 | 102 | 95 | 27 | 25 | 164 | 69 | n/d | n/d | n/d | n/d |
8 | M | 42 | 1 | 0 | 0 | 1 | 6 | 3 | 7.8 | 119 | 101 | 31 | 29 | 320 | 148 | 11 | 6 | 2.05 | 1.28 |
9 | M | 41 | 1 | 0 | 0 | 1 | 4 | 6 | 7.4 | 96 | 88 | 27 | 26 | 97 | 111 | 18 | 6 | 5.92 | 1.47 |
10 | M | 42 | 1 | 5 | 0 | 1 | 5 | 5 | 7.6 | 101 | 89 | 27 | 25 | 65 | 78 | 15 | 9 | 3.07 | 1.80 |
11 | F | 49 | 2 | 0 | 0 | 3 | 3 | 4 | 4.4 | 90 | 85 | 26 | 25 | 67 | 31 | 23 | 17 | 6.24 | 4.53 |
12 | F | 47 | 1 | 0 | 0 | 2 | 6 | 4 | 4.5 | 114 | 100 | 38 | 36 | 151 | 79 | 33 | 18 | 14.5 | 4.40 |
13 | M | 67 | 1 | 25 | 5 | 2 | 3 | 5 | 2.5 | 93 | 82 | 24§ | 23 | 176 | 164 | 12 | 13 | 2.40 | 3.06 |
14 | F | 29 | 3 | 5 | 5 | 2 | 3 | 6 | 3.9 | 74 | 70 | 21¶ | 20 | 179 | 86 | 14 | 8 | 3.05 | 1.74 |
15 | F | 43 | 3 | 5 | 5 | 3 | 1 | 2 | 2.4 | 104 | 101 | 40 | 39 | 147 | 81 | n/d | n/d | n/d | n/d |
16 | F | 50 | 3 | 0 | 0 | 1 | 2 | 3 | 4.0 | 90 | 85 | 34 | 32 | 53 | 48 | 17 | n/d | 4.08 | n/d |
17 | F | 51 | 1 | 10 | 10 | 2 | 3 | 7 | 3.8 | 116 | 112 | 37 | 36 | 334 | 320 | 29 | 18 | 5.80 | 3.04 |
18 | M | 45 | 1 | 10 | 0 | 1 | 1 | 4 | 9.5 | 105 | 97 | 31 | 28 | 94 | 68 | 15 | 12 | 3.87 | 2.83 |
19 | M | 33 | 1 | 0 | 0 | 1 | 3 | 3 | 2.6 | 102 | 97 | 29 | 28 | 57 | 47 | 12 | 14 | 2.61 | 3.05 |