Clinical features of Brazilian patients with autoimmune hepatitis with and without antibodies to soluble liver antigen/liver pancreas (SLA/LP) antigen
| Clinical features | AIH type 1 SLA/LP positive (n=23) | AIH type 1 SLA/LP negative (n=93) | AIH type 2 (n=16) |
|---|---|---|---|
| NV, normal value; for other abbreviations see table 1. | |||
| Skin colour | |||
| White | 12 (52%) | 37 (40%) | 10 (63%) |
| Mulatto | 9 (39%) | 38 (41%) | 5 (31%) |
| Black | 2 (8%) | 14 (15%) | 1 (6%) |
| Japanese descendant | 0 | 4 (4%) | |
| Sex | |||
| Male | 0 | 19 (20%) | 2 (13%) |
| Female | 23 | 74 (80%) | 14 (88%) |
| Age of onset (y) | |||
| 0–15 | 7 (30%) | 44 (47%) | 11 (69%) |
| 15–30 | 5 (22%) | 17 (18%) | 4 (25%) |
| 30–50 | 11 (48%) | 19 (21%) | 1 (6%) |
| 50–70 | 0 | 13 (14%) | 0 |
| AST (×NV) | |||
| 0–5 | 5 (22%) | 11 (12%) | 3 (19%) |
| 5–10 | 4 (17%) | 11 (12%) | 3 (19%) |
| >10 | 14 (61%) | 71 (76%) | 10 (62%) |
| γ-globulins (×NV) | |||
| 1.0–1.5 | 2 (9%) | 15 (16%) | 3 (19%) |
| 1.5–2.0 | 6 (26%) | 17 (18%) | 8 (50%) |
| ≥2.0 | 15 (65%) | 61 (66%) | 5 (32%) |
| Total bilirubins (mg%) | |||
| 0–5 | 17 (74%) | 38 (41%) | 6 (38%) |
| 5–10 | 5 (22%) | 29 (31%) | 5 (31%) |
| >10 | 1 (4%) | 23 (25%) | 5 (31%) |
| Cirrhosis at diagnosis | 8/17 (47%) | 68/93 (63%) | 8/14 (57%) |