Appearance of gross bleeding in mice (%) during dextran sodium sulphate treatment.
| Homozygous transgenic | Heterozygous transgenic | Wild-type | |
|---|---|---|---|
| Significance was calculated using a χ2 test. All values were compared with wild-type mice: *p<0.05, **p<0.01, ***p<0.001. | |||
| Day 0 | 0 (n=36); NS | 0 (n=38); NS | 0 (n=30) |
| Day 1 | 0 (n=36); NS | 0 (n=38); NS | 0 (n=30) |
| Day 2 | 6 (n=36); NS | 0 (n=38); NS | 0 (n=30) |
| Day 3 | 25 (n=36);** | 3 (n=38); NS | 0 (n=30) |
| Day 4 | 80 (n=35);*** | 19 (n=38); NS | 6 (n=30) |
| Day 5 | 100 (n=17);*** | 61 (n=19); NS | 38 (n=15) |
| Day 6 | 100 (n=17);*** | 78 (n=19);* | 50 (n=15) |
| Day 7 | 100 (n=5); NS | 100 (n=19);* | 75 (n=15) |
| Day 8 | ND (n=0) | 100 (n=13); NS | 100 (n=10) |