Effect of oral (JO 2871 and BMY 14802) and intravenous (cyclosomatostatin (CSS)) administration on gastric emptying (GE) and intestinal transit in mice
| Gastric emptying (GE) (%) | Intestinal transit (GC units) | |
|---|---|---|
| Values for GE and geometric centre (GC) were determined 60 minutes after oral (PO) JO 2871 and BMY 14802 administration and 30 minutes after CSS intravenous (IV) administration. | ||
| Vehicle (saline 0.2 ml PO) | 44.8 (5.1) | 6.6 (0.3) |
| JO 2871 (1000 μg/kg PO) | 45.1 (4.9) | 6.4 (0.3) |
| BMY 14802 (1000 μg/kg PO) | 43.7 (4.4) | 5.9 (0.4) |
| CSS (1 μg/kg IV) | 44.2 (4.8) | 6.2 (0.1) |