Table 3

Number of patients with iron overload* in relation to genotype

C282YH63DS65CTotal No of patientsNo of patients in whom data missingPatients with iron overload*
*Patients with iron staining of at least grade 1 on liver biopsy or treated with repeated phlebotomies.
†p<0.05 compared with patients without mutations in the HFE gene (Fisher’s exact test).
+/+−/−−/−841958/65 (89%)†
−/−+/+−/−72 3/5 (60%)
+/−+/−−/−21513/16 (81%)†
+/−−/−+/−20 1/2 (50%)
−/−+/−+/−30 2/3 (67%)
+/−−/−−/−2813 5/15 (33%)
−/−+/−−/−491217/37 (46%)†
−/−−/−+/−90 4/9 (44%)
−/−−/−−/−931418/79 (23%)