Number of patients with iron overload* in relation to genotype
| C282Y | H63D | S65C | Total No of patients | No of patients in whom data missing | Patients with iron overload* |
|---|---|---|---|---|---|
| *Patients with iron staining of at least grade 1 on liver biopsy or treated with repeated phlebotomies. | |||||
| †p<0.05 compared with patients without mutations in the HFE gene (Fisher’s exact test). | |||||
| +/+ | −/− | −/− | 84 | 19 | 58/65 (89%)† |
| −/− | +/+ | −/− | 7 | 2 | 3/5 (60%) |
| +/− | +/− | −/− | 21 | 5 | 13/16 (81%)† |
| +/− | −/− | +/− | 2 | 0 | 1/2 (50%) |
| −/− | +/− | +/− | 3 | 0 | 2/3 (67%) |
| +/− | −/− | −/− | 28 | 13 | 5/15 (33%) |
| −/− | +/− | −/− | 49 | 12 | 17/37 (46%)† |
| −/− | −/− | +/− | 9 | 0 | 4/9 (44%) |
| −/− | −/− | −/− | 93 | 14 | 18/79 (23%) |