Duration, severity, and frequency of gastro-oesophageal reflux disease symptoms* in 58 case subjects and 106 control subjects
| Heartburn | Acid regurgitation | Dysphagia | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | OR† | p Value | Cases | Controls | OR† | p Value | Cases | Controls | OR† | p Value | |
| *Symptom refers to heartburn, acid regurgitation, or dysphagia. | ||||||||||||
| †Crude odds ratio computed without taking any other risk factors into account. | ||||||||||||
| Symptom* in previous year | 71% | 84% | 0.46 | 0.071 | 60% | 76% | 0.49 | 0.065 | 52% | 41% | 1.57 | 0.226 |
| Symptom onset | ||||||||||||
| Past year | 2% | 8% | 0.072 | 13% | 17% | 0.381 | 27% | 21% | 0.255 | |||
| 1–5 y ago | 15% | 24% | 2.33 | 16% | 27% | 0.76 | 33% | 53% | 0.48 | |||
| 5–10 y ago | 13% | 23% | 2.10 | 24% | 22% | 1.40 | 18% | 7% | 2.00 | |||
| >10 y ago | 69% | 45% | 5.43 | 47% | 33% | 1.87 | 21% | 19% | 0.88 | |||
| Symptom frequency | ||||||||||||
| Everyday | 12% | 33% | 0.005 | 8% | 13% | 0.416 | 25% | 23% | 0.056 | |||
| >1×/week | 23% | 32% | 2.07 | 13% | 25% | 0.92 | 16% | 16% | 0.89 | |||
| 1×/week | 12% | 14% | 2.42 | 18% | 16% | 1.97 | 9% | 27% | 0.31 | |||
| 1×/month | 33% | 12% | 7.38 | 26% | 18% | 2.44 | 12% | 20% | 0.55 | |||
| <1×/month | 21% | 9% | 6.53 | 36% | 27% | 2.33 | 38% | 11% | 3.00 | |||
| Symptom severity | ||||||||||||
| Mild | 43% | 17% | 0.006 | 31% | 31% | 0.731 | 37% | 21% | 0.129 | |||
| Moderate | 48% | 60% | 0.32 | 51% | 45% | 1.16 | 37% | 60% | 0.35 | |||
| Severe | 9% | 22% | 0.17 | 18% | 24% | 0.77 | 27% | 9% | 0.82 | |||
| Symptom awakens at night | 43% | 57% | 0.58 | 0.136 | 45% | 51% | 0.78 | 0.558 | ||||
| Improved with antacids | 74% | 70% | 1.08 | 0.905 | 63% | 56% | 0.95 | 0.864 | ||||