Table 7

HFE mutations, serum ferritin, and transferrin saturation in members of a family carrying the C282Y and S65C mutations

Family memberHFE mutationHb (g/l)TS (%)Serum ferritin (μg/l)ALT (U/l)Iron staining at liver biopsy
Hb, haemoglobin concentration; TS, transferrin saturation; ALT, alanine aminotransferases; ND, not determined.
FatherC282Y/C282Y15493%131134Grade 4
MotherS65C/S65C12217%816ND
Son (26 years old)C282Y/S65C15251%10629ND
Son (24 years old)C282Y/S65C15877%23819Grade 1