Table 2

Relationship between the presence of gastric lesions and Helicobacter pylori positivity and the degree of mucosal atrophy in patients with familial adenomatous polyposis

Fundic gland polyposisGastric adenoma
Positive (n=16)Negative (n=15)p ValuePositive (n=12)Negative (n=19)p Value
PG, pepsinogen.
*Fisher’s exact probability test.
†Mann-Whitney U test.
H pylori positive cases 2 (13%)10 (67%)<0.005* 7 (58%) 5 (26%)0.08*
PG I (ng/ml)46.3 (14.2)44.9 (19.5) 0.50†42.0 (20.6)48.0 (13.9)0.16†
PG II (ng/ml) 9.2 (3.7)17.5 (12.3) 0.11†14.6 (8.9)12.3 (10.4)0.39†
PG I/PG II ratio 5.4 (1.6) 3.4 (1.7)<0.005† 3.3 (1.2) 5.2 (2.0)<0.01†
Histological atrophy score
    Antrum 0.7 (0.7) 1.5 (0.7)<0.005† 1.4 (1.0) 0.9 (0.7)0.13†
    Corpus 0.2 (0.4) 1.0 (0.8)<0.005† 0.9 (0.8) 0.4 (0.6)<0.05†