Duodenal reflux exposure parameters during treatment with omeprazole 20 mg twice daily and with omeprazole 20 mg twice daily plus baclofen 10 mg three times daily
| Variable | Period | Omeprazole | Omeprazole + baclofen | p Value |
|---|---|---|---|---|
| Values are median (interquartile range). | ||||
| % Time absorbance >0.14 | Total | 13.8 (11.8; 15.5) | 6.1 (0.8; 10.4) | <0.005 |
| Upright | 16 (10.9; 21.9) | 8.6 (1.3; 16.4) | 0.06 | |
| Supine | 11.2 (0.9; 18.4) | 0 (0; 1.1) | <0.05 | |
| No of duodenal reflux episodes | Total | 23 (14.5; 33) | 12 (5; 21) | 0.06 |
| Upright | 17 (10; 25) | 12 (1; 20) | 0.07 | |
| Supine | 4.5 (0.7; 8.2) | 0 (0; 0) | <0.05 | |
| No of duodenal reflux episodes lasting >5 min | Total | 5 (3; 8) | 2 (0.5; 4.5) | <0.05 |
| Upright | 4 (2.5; 5) | 2 (0.5; 4) | 0.06 | |
| Supine | 2 (0.5; 2) | 0 (0; 0) | <0.05 | |