ISR5 (pmol min/m2) | Slope5 (pmol min/m2/ mM) | p6 (pmol m2/ mM) | p4 (pmol min/m2) | SDr (pmol min/m2) | ISRtot (nmol/m2) | |
---|---|---|---|---|---|---|
ISR5, insulin secretion at 5 mM glucose; Slope5, of the dose-response at 5 mM glucose; p6, parameter of the derivative component (eq 2); p4, amplitude of the 24 hour modulation (eq 1); SDr, standard deviation of the residual insulin secretion component (Sr(t), Eq. 3); ISRtot, 24 hour integral of insulin secretion. *p<0.02 or less versus control subjects. †0.08<p<0.12 versus control subjects. | ||||||
Controls | 57 (5) | 43 (6) | 1327 (425) | 35 (11) | 32 (6) | 138 (11) |
Cirrhotics | 175 (26)* | 112 (34)† | 5385 (1586)* | 84 (27)† | 108 (21)* | 295 (53)* |