Table 2

Standardised incidence ratios (SIR) and 95% confidence intervals (CI) for pancreatic cancer among patients who were hospitalised for alcoholism, alcoholic chronic pancreatitis, non-alcoholic chronic pancreatitis, alcoholic liver cirrhosis, and non-alcoholic liver cirrhosis during 1965–1994, Sweden*

DeterminantAlcoholismAlcoholic chronic pancreatitisNon-alcoholic chronic pancreatitisAlcoholic liver cirrhosisNon-alcoholic liver cirrhosis
Obs†SIR95%CIObs†SIR95%CIObs†SIR95%CIObs†SIR95%CIObs†SIR95%CI
*Excluding the first year of follow up.
†Observed number of cancer cases.
‡Person time before the onset of diabetes mellitus was allocated to non-diabetes mellitus stratum.
Total3051.41.2 –1.57 2.2 0.9– 4.574 8.7 6.8–1 0.9271.91.3– 2.8111 .20.6– 2.2
Sex
    Male2541.31.2–1.54 1.4 0.4–3.751 9.9 7.4–13.1222.01.3–3.151.20.4–2.8
    Female511.61.2–2.13 7.3 1.5–21.423 6.7 4.3–10.151.60.5–3.761.30.5–2.8
    p value0.25 0.02 0.110.620.90
Follow up duration (y)
    1–4821.31.0–1.64 3.8 1.0–9.65618.013.6–23.491.50.7–2.930.80.2–2.3
    5–9911.41.1–1.72 2.0 0.2–7.212 4.5 2.3–7.9133.11.7–5.310.40.01–2.2
    10+1321.51.2–1.81 0.9 0.02–5.06 2.1 0.8–4.751.30.4–3.072.81.1–5.7
    10–14781.51.2–1.9
    15–30541.41.1–1.8
    p value for trend0.35 0.16<0.010.990.04
Age at index discharge (y)
    <501071.71.4–2.12 1.7 0.2–6.29 8.1 3.7–15.431.70.3–4.810.90.02–4.8
    50–59911.21.0–1.54 3.5 0.9–8.92410.0 6.4–14.9132.91.5–4.941.80.5–4.6
    60–69811.31.1–1.61 1.5 0.04–8.23211.9 8.1–16.781.50.6–2.951.60.5–3.7
    ≥70261.10.7–1.609 3.8 1.8–7.331.40.3–4.110.40.01–2.4
    p value for trend0.02 0.77 0.120.350.50
Diabetes mellitus‡
    No2821.41.2–1.57 3.2 1.3–6.663 8.8 6.8–11.3211.81.1–2.881.10.5–2.1
    Yes231.71.1–2.6011 7.7 3.9–13.862.40.9–5.232.10.4–6.1
    p value0.29 0.07 0.680.560.32