Results with autofluorescence (AF) and methylene blue (MB) staining compared with histological findings as the reference standard in the 35 patients with Barrett’s osophagus (BO); the results of video endoscopy (VE) alone are also shown (with respect to the respective accuracy achieved, no statistically significant differences were found among the different methods used)
| Histolopathological diagnosis* per patient | n | Method | AF | MB | VE alone |
|---|---|---|---|---|---|
| *Most advanced diagnoses per patient—that is, a patient with 10 normal biopsies, four LGD, and one HGD is a “HGD patient”. | |||||
| HGD, high grade dysplasia; LGD, low grade dysplasia. | |||||
| Cancer | 8 | True positive | 3 (38%) | 6 (75%) | 7 (88%) |
| HGD | 1 | True positive | 1 (100%) | 1 (100%) | 1 (100%) |
| LGD | 8 | True positive | 3 (38%) | 3 (38%) | 4 (50%) |
| Normal BO | 18 | True negative | 14 (78%) | 9 (50%) | 11 (61%) |