Disease free survival (univariate Cox’s regression model)
| Variable | Category | RR | 95% CI | p Value |
|---|---|---|---|---|
| RR, risk ratio; CI, confidence interval; LOH, loss of heterozygosity. | ||||
| BRCA1 LOH | Positive v negative | 2.54 | 1.45–4.48 | 0.001 |
| Vascular invasion | Yes v no | 1.33 | 0.76–2–36 | 0.31 |
| Tumour side | Left v right | 1.35 | 0.6–3 | 0.46 |
| Rectum v right | 1.31 | 0.66–3 | 0.52 | |
| Stage | II v I | 1.07 | 0.38–3 | 0.88 |
| III v I | 2.43 | 0.94–6.26 | 0.05 | |
| Tumour differentiation | Moderate v well | 1.09 | 0.57–2.08 | 0.78 |
| Poor v well | 1.64 | 0.75–3.60 | 0.21 | |
| Lymph node metastases | 1–3 v 0 | 1.90 | 1.02–3.54 | 0.04 |
| ⩾4 v 0 | 3.44 | 1.63–7.25 | 0.001 | |